From Cancer Progress 2022

Moderator: Jeffrey M. Bockman, PhD, EVP, BioConsulting, Head of Oncology, Lumanity

Panelists:

  • Jennifer Buell, PhD, President & CEO, MiNK Therapeutics
  • Michael A Curran, PhD, Associate Professor, Dept. of Immunology
  • Björn Frendéus, PhD, CSO, BioInvent
  • Axel Hoos, MD, PhD, CEO, Scorpion Therapeutics
  • Andrew Pierce, PhD, VP of Translational Biology, Crescendo Biologics Ltd
  • Peter Sandor, MDA, MBA, SVP, Primary Focus Lead Immuno-oncology, Astellas
  • Emmett Schmidt, MD, PhD, VP, Clinical Oncology, Lead, External Collaborations Oncology Early Development, Merck and Co
  • Dmitriy Zamarin, MD, PhD, Translational Research Director, Gynecologic Medical Oncology, Memorial Sloan Kettering Cancer Center

We have now had a decade of R&D directed towards improving on the applicability and activity of combinations with checkpoint inhibitors (CPIs). There have been many ups and downs, and a few surprises along the way, not the least of which is the combination value of CPIs with chemotherapy and with MTKIs, but not so much with other IO agents.  While this may be finally about to change with TIGIT, LAG3, and IL-2 programs to name a few marquee examples, questions still remain on when, where, what and how best to combine CPIs. This session brings together a stellar, and large, cats of experts across the BioPharma industry, from academic researchers and clinical trialists to biotechs to large pharma, to have a dialogue, maybe even a debate, on this complex and fascinating topic.